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In contrast, mitochondrial PRDX3 undergoes hyperoxidation during lipid peroxidation stress and translocates to the plasma membrane, where it suppresses cystine uptake, depletes intracellular GSH, and amplifies ferroptotic execution 114

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10.1007/s12020-018-1708-z 31 LingvayI.BauerR.Baker-KnightJ.LawsonJ.PratleyR

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GLP-1 drugs are generally safe but monitored